English Transcript (中文全文在下方阅读)
AMANDA: Alright Dr. Lio, we just have a few questions left. One of our community members heard that some patients do not do well even on respirators. They are wondering: why do some patients continue to have low blood oxygen saturation despite being on ventilators? Did those patients pass away due to an intrinsic problem with their blood in addition to being infected with COVID?
DR. LIO: So, oxygen has to be able to go from your mouth into your lungs, and from your lungs into the blood itself. There are different barriers that can get in the way of that. If you have fluid in those air sacs within the lungs, the oxygen can get up to that point, but it is not going to easily pass that fluid into the bloodstream. So you can imagine, even though you are on a ventilator, that ventilator is pushing air, pushing extra oxygen into the lungs. If there is a lot of fluid in the lungs in the first place, it doesn’t matter how much oxygen you push in, it’s not going into the blood. Something else that might happen is that even if you have that air sac and it’s open, oxygen is getting there, there might not be enough blood flow going to that part of the lung. So, if the blood flow is going to the part of the lung that is not getting much oxygen, then you’ll still have problems with having oxygen in the blood. When you don’t have enough oxygen in the blood, and all of your tissues require that in order to survive, that’s when things will start getting worse for you.
中文视频全文
阿曼达：好的刘医生，我们只剩下几个问题。一些社区居民听说，有些患者即使使用呼吸器也效果不佳。 他们想知道：为什么一些患者尽管使用了呼吸机，血氧饱和度仍然较低？除感染新冠外，这些患者是否因血液内在的问题而死亡？
刘医生：氧气必须能够从口腔进入肺部，然后从肺部进入血液本身。这个过程中存在一些可能的阻碍。如果肺内气囊中有液体，氧气是可以进到肺里，但不能轻易绕过积液输送到血流中。因此，你可以想象，即使你使用呼吸机，呼吸机推动空气，将额外的氧气推入肺部， 但是如果肺部有大量积液，不管你推入多少氧气，都不会进入血液。还有一种情况是，即使你的气囊是开放的，氧气也可以到达那里，但是你没有足够的血流流向肺的这部分。如果血流流到了肺中没有太多氧气的其他部分，那你还是无法为血液供氧。当你的血液中没有足够的氧气，然而你的所有组织都需要氧气才能生存，那你的情况就可能会变得更糟。